Online forum for Physiologists
HomeGalleryCalendarFAQSearchRegisterMemberlistUsergroupsLog in

Share | 

 Action potential-activated calcium current

Go down 

Number of posts : 241
Registration date : 2007-01-07

PostSubject: Action potential-activated calcium current   Wed Dec 30, 2009 4:50 pm

The current physiology teaching is that extracellular calcium is not required for skeletal muscle contraction. Depolarization of the t-tubule stimulates the dihydropyridine receptors (DHPR) and this results in calcium release from the sarcoplasmic reticulum (SR). This process is called voltage induced calcium release or VICR. This is in contrast to the cardiac muscle where calcium entry through the t-tubules during depolarization causes calcium release from the SR (calcium induced calcium release or CICR). Now it has been reported that calcium enters the skeletal muscle during depolarization. This calcium current is called action potential-activated calcium current or APACC. The physiological role of this calcium entry during depolarization is yet to be understood.

Read more in the links given below:
Back to top Go down
View user profile
Action potential-activated calcium current
Back to top 
Page 1 of 1
 Similar topics
» Current Workload Relative to Capacity
» Rev. Sun Myung Moon is dying - current big cult story unfolding
» Wikimapia: Current & Former British Military Establishments
» NEW MEMBERS: After joining... your account will be activated within 24 hours!!
» A Current Affair Tuesday 26th July - New non-invasive weight loss surgery...

Permissions in this forum:You cannot reply to topics in this forum
Physiology :: Journals-
Jump to: